Mister (Mr.) Wayne is a teacher and school guidance counselor at Bailey Downs High School.
Although it is not explicitly shown in film, Mr. Wayne was possibly a social studies/geography or history teacher at Bailey Downs High School. Interestingly, he also serves as a guidance counselor at the school, having his own office.
The first scene depicting the sisters in public (apart from their taking pictures outside) is in Mr. Wayne's classroom. He appears visibly disgusted by the sister's presentation choice in response to the prompt "Life in Bailey Downs." This further angers the sisters who already distrusted the students and teachers at Bailey Downs High and reinforces their beliefs that they shouldn't approach their teachers/grown-ups for any advice.
His death caused by Ginger Fitzgerald could pinpoint when Ginger started to get out of control, and could be the point where Brigitte truly understands how serious the situation has become (where Ginger had previously murdered Norman the dog and presumably Morley, now she has murdered a teacher, followed by the janitor).